Ngwaahịa

Ngwaahịa PO nwere mmetụta dị mma na-egbochi ọnyà na mgbochi itching, usoro ihe mgbochi pụrụ iche, ezigbo solubility na recombination, nchekwa, na-adịghị egbu egbu, na-adịghị ewe iwe, na-ejikarị na shampoo na ntutu isi ngwaahịa.PO nwere mmetụta antipruritic magburu onwe ya, ma nweekwa sterilization na deodorization ọrụ, n'ihi ya, a na-eji ya na mmiri ịsa ahụ iji nweta nsonaazụ dị mma.PO nwere mmetụta igbu ọchụ sara mbara na fungi na ebu, ma nwee mmetụta ọgwụgwọ dị mma na ụkwụ na mgbanaka aka.Enwere ike iji ya dị ka ihe nchekwa na ihe ịchọ mma, dị ka nje bacteria n'ime ncha, yana dịka ihe na-eme ka ọkpụkpụ.Ya mere, PO bụ multifunctional mgbochi dandruff na antipruritic bactericide, nke a na-ejikarị eme ihe na ncha ntutu na ngwaahịa nlekọta ntutu isi, lotions bath, cosmetics, na detergents.

Piroctone olamine, nnu ethanolamine nke hydroxamic acid sitere na Piroctone, bụ onye na-ahụ maka mgbochi mycotic hydroxypyridone.Piroctone olamine na-abanye n'ime akpụkpọ ahụ cell wee mepụta ogige ndị nwere ion ígwè, na-egbochi ike metabolism na mitochondria[1].Piroctone olamine (PO) bụ nnu ethanolamine nke sitere na piroctone sitere na hydroxamic acid.Ọrịa Candida niile na-egosi mkpokọta inhibitory kacha nta (MICs) maka Piroctone olamine (0.125-0.5 μg/mL) na Amphotericin B (AMB) (0.03-1 μg/mL).

Ọrụ a bụ iji nyochaa ọrụ antifungal nke Piroctone olamine na ọgwụgwọ nke intra-abdominal candidiasis n'ụdị nnwale site na iji ụmụ oke Switzerland.A na-eme ọgwụgwọ ya na Piroctone olamine (0.5 mg / kg) awa 72 mgbe nchịkwa intraperitoneal butere ya.Maka ntụnyere, a na-emeso otu anụmanụ (n=6) na Amphotericin B (0.5 mg/kg).A na-eme nchọpụta mycological site na ịnakọta imeju, splin na akụrụ.A na-enyocha data gbasara uto fungal na ọnwụ anwụ site na nyocha nke Student na nyocha nke iche, yana ọkwa dị mkpa atọrọ na P.<0.05.Ọdịiche dị na akara uto fungal n'etiti ndị na-ahụ maka njikwa na ndị otu ọgwụgwọ (Piroctone olamine na Amphotericin B) dị ịrịba ama (P).<0.05)